سیویلیکا را در شبکه های اجتماعی دنبال نمایید.

Clinico-epidemiology of washing powder (‘Prinso’) poisoning in Sri Lanka

سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 184

فایل این مقاله در 7 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:

شناسه ملی سند علمی:

JR_PJMT-11-2_003

تاریخ نمایه سازی: 8 تیر 1401

چکیده مقاله Clinico-epidemiology of washing powder (‘Prinso’) poisoning in Sri Lanka

Background: ‘Prinso’ is a fabric stain remover, which is consisted of two sachets, one containing brown crystals (potassium permanganate) and the other white granules (calcium oxalate). The product is made by small scale manufacturers of Sri Lanka and has become popular as a remover of stains. Recently, deliberate self-poisoning with ‘Prinso’ has become common in both rural and urban areas of Southern Province of Sri Lanka.Methods: A prospective clinical study was conducted in Teaching Hospital Ratnapura, Sri Lanka over 3 years commencing from July 2017. Epidemiological data, clinical features, treatments, and outcomes were collected. The data were analyzed through SPSS software version 21, using descriptive statistics.Results: There were 274 (9.5%) patients with ‘Prinso’ poisoning out of which 140 (51%) were males and 134 (49%) were females. All were deliberate self-poisonings and 117 (43%) ingested oxalate alone; 31 (11%) ingested only permanganate, and 126 (46%) ingested both chemicals. The age ranged from 13-80 years (mean 31.6 ± 14 years) and the most commonly affected age group was 12-31 years (165;60%). The majority of patients were unemployed (108;39%) and 22 (8%) schooling children. Most patients (n=145;53%) were admitted to hospital within 1-4 hour of the ingestion (median 2 hrs and IQR 2-4 hrs) from Ratnapura (n=74;27%). Most of them (n=78;28.5%) were treated at hospital for 3 days (mean 4.8 days, IQR 2-6 days). Decontamination was done for 88% (n=239). Gastrointestinal symptoms including nausea (n=90;33%), vomiting (n=193;70%) and epigastric pain (n=141;52%) occurred frequently. The main complications among the patients were acute kidney injury [AKI] (110;40%), hypocalcemia (38;14%), hypotension (29;11%), ECG changes (27;10%), and methemoglobinemia (26;9.5%). Hemodialysis was done for 39 (14%) and 20 (7%) were treated at intensive care unit from which 13 (5%) were intubated. Methylene blue (antidote) was given to 25 (9%). Leukocytosis was observed in 118 (43%) patients and 236 (86%) were recovered. Despite medical attempts, 22 (8%) died. Case fatality rate for ‘Prinso’ poisoning was found to be 6.6% (90% CI 2.3-13.4;P < 0.05).Conclusions: ‘Prinso’ is a deadly poisoning household agent and AKI is the most common clinical manifestation.  

کلیدواژه های Clinico-epidemiology of washing powder (‘Prinso’) poisoning in Sri Lanka:

نویسندگان مقاله Clinico-epidemiology of washing powder (‘Prinso’) poisoning in Sri Lanka

R.M.M.K.Namal Rathnayaka

Department of Pharmacology, Faculty of Medicine, Sabaragamuwa University of Sri Lanka, Hidellana, Ratnapura, Sri Lanka. Intensive Care Unit, Teaching Hospital, Ratnapura, Sri Lanka. Department of Veterinary Pathobiology, Faculty

P.E.A.N. Ranathunga

Medical Unit, Teaching Hospital, Ratnapura.

مراجع و منابع این مقاله:

لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :
Anonymous (۱۹۹۸). Medical Statistic Unit, Annual Health Statistics ۱۹۹۸. Ministry ...
Eddleston M, Sudarshan K, Senthilkumaran M, Reginald K, Karalliedde L, ...
Manuel C, Gunnell DJ, van der Hoek W, Dawson A, ...
Fernando R. The National Poison Information Centre in Sri Lanka: ...
Van der Hoek W, Konradsen F. Analysis of ۸۰۰۰ hospital ...
Eddelston M. Choice of poison for intentional self-poisoning in rural ...
Namal Rathnayaka RMMK, Ranathunga PEAN, Fernando R. Epidemiology and clinical ...
Munasinghe M, Fernando W. The toxic laundry powder “Prinso” is ...
Gawarammana IB, Ariyananda PL, Palangasinshe C, de Silva NGL, Fernando ...
Herath N, Kodithuwakku G, Delumgahawaththa S, Abeyratne D, Weerakoon K. ...
De Silva VA, Senanayake SM, Dias P, Hanwella R. From ...
The University of Oxford. Chemical and other safety information. Safety ...
Fernando R. Management of Poisoning. ۲۰۰۷, The national Poisons Information ...
Dassanayake U, Gnanathasan CA. Acute renal failure following oxalic acid ...
The University of Oxford. Chemical and other safety information. Safety ...
Middleton SJ, Jacyna M, McClaren D, Robinson R, Thomas HC. ...
Namal Rathnayaka RMMK, Ranaweera J, Kumarasinghe KDM, Ranathunga PEAN, Gunathilaka ...
Mahomedy MC, Mahomedy YH, Canham PA, Downing JW, Jeal DE. ...
Ong KL, Tan TH, Cheung WL. Potassium permanganate poisoning-a rare ...
Kochhar R, Das K, Mehta SK. Potassium permanganate induced oesophageal ...
Dagli AJ, Golden D, Finkel M, Austin E. Pyloric stenosis ...
Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work ...
Konta T, Yamaoka M, Tanida H, Matsunaga T, Tomoike H. ...
Shihana F, Dissanayake DM, Buckley NA, Dawson AH. A Simple ...
Nadikuda SK, Venkategowda PM, Rao SM, Kondala R. Effective Approach ...
Dawson AH, Eddleston M, Senarathna L, Mohamed F, Gawarammana I, ...
Cao LC, Honeyman TW, Cooney R, Kennington L, Scheid CR, ...
نمایش کامل مراجع