Clinico-epidemiology of washing powder (‘Prinso’) poisoning in Sri Lanka
سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 177
فایل این مقاله در 7 صفحه با فرمت PDF قابل دریافت می باشد
- صدور گواهی نمایه سازی
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_PJMT-11-2_003
تاریخ نمایه سازی: 8 تیر 1401
چکیده مقاله:
Background: ‘Prinso’ is a fabric stain remover, which is consisted of two sachets, one containing brown crystals (potassium permanganate) and the other white granules (calcium oxalate). The product is made by small scale manufacturers of Sri Lanka and has become popular as a remover of stains. Recently, deliberate self-poisoning with ‘Prinso’ has become common in both rural and urban areas of Southern Province of Sri Lanka.Methods: A prospective clinical study was conducted in Teaching Hospital Ratnapura, Sri Lanka over ۳ years commencing from July ۲۰۱۷. Epidemiological data, clinical features, treatments, and outcomes were collected. The data were analyzed through SPSS software version ۲۱, using descriptive statistics.Results: There were ۲۷۴ (۹.۵%) patients with ‘Prinso’ poisoning out of which ۱۴۰ (۵۱%) were males and ۱۳۴ (۴۹%) were females. All were deliberate self-poisonings and ۱۱۷ (۴۳%) ingested oxalate alone; ۳۱ (۱۱%) ingested only permanganate, and ۱۲۶ (۴۶%) ingested both chemicals. The age ranged from ۱۳-۸۰ years (mean ۳۱.۶ ± ۱۴ years) and the most commonly affected age group was ۱۲-۳۱ years (۱۶۵;۶۰%). The majority of patients were unemployed (۱۰۸;۳۹%) and ۲۲ (۸%) schooling children. Most patients (n=۱۴۵;۵۳%) were admitted to hospital within ۱-۴ hour of the ingestion (median ۲ hrs and IQR ۲-۴ hrs) from Ratnapura (n=۷۴;۲۷%). Most of them (n=۷۸;۲۸.۵%) were treated at hospital for ۳ days (mean ۴.۸ days, IQR ۲-۶ days). Decontamination was done for ۸۸% (n=۲۳۹). Gastrointestinal symptoms including nausea (n=۹۰;۳۳%), vomiting (n=۱۹۳;۷۰%) and epigastric pain (n=۱۴۱;۵۲%) occurred frequently. The main complications among the patients were acute kidney injury [AKI] (۱۱۰;۴۰%), hypocalcemia (۳۸;۱۴%), hypotension (۲۹;۱۱%), ECG changes (۲۷;۱۰%), and methemoglobinemia (۲۶;۹.۵%). Hemodialysis was done for ۳۹ (۱۴%) and ۲۰ (۷%) were treated at intensive care unit from which ۱۳ (۵%) were intubated. Methylene blue (antidote) was given to ۲۵ (۹%). Leukocytosis was observed in ۱۱۸ (۴۳%) patients and ۲۳۶ (۸۶%) were recovered. Despite medical attempts, ۲۲ (۸%) died. Case fatality rate for ‘Prinso’ poisoning was found to be ۶.۶% (۹۰% CI ۲.۳-۱۳.۴;P < ۰.۰۵).Conclusions: ‘Prinso’ is a deadly poisoning household agent and AKI is the most common clinical manifestation.
کلیدواژه ها:
نویسندگان
R.M.M.K.Namal Rathnayaka
Department of Pharmacology, Faculty of Medicine, Sabaragamuwa University of Sri Lanka, Hidellana, Ratnapura, Sri Lanka. Intensive Care Unit, Teaching Hospital, Ratnapura, Sri Lanka. Department of Veterinary Pathobiology, Faculty
P.E.A.N. Ranathunga
Medical Unit, Teaching Hospital, Ratnapura.
مراجع و منابع این مقاله:
لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :