Prognostic value of myocardial perfusion imaging in Iranian patients using total perfusion deficits: Comparison with semi-quantitative assessment

Introduction: Considering that quantitative methods are usually more reproducible with lower inter-observer variability, the purpose of this research was to compare the prognostic value of the two quantitative method with quantitative perfusion SPECT (QPS) software. Methods: This study was performed prospectively and included ۲۰۰ participants who were referred for myocardial perfusion imaging. These participants were selected by the convenience sampling method. All patients were followed up after one year. Patients were classified as those with and without major cardiac events, including cardiac death, non-fatal myocardial infarction, open-heart surgery, abnormal angiographic findings, and unstable angina.Results: There were ۶۲ male (۳۱.۰%) and ۱۳۸ female (۶۹.۰%) patients, ranging in age from ۳۰ to ۸۶ years. The results indicated that the major cardiac events were significantly higher in moderate and severe categories based on summed stress score (SSS) (P=۰.۰۲۴) and total perfusion deficit (TPDs) (P=۰.۰۰۲) scores. SSS score with TPDs score (P = ۰.۷۶۴), summed rest score (SRS) with TPDr score (P = ۰.۵۸۳) and SDS with ΔTPD (P = ۰.۱۱۸) were compatible for predicting major heart events within a year.Conclusion: Total perfusion deficits obtained from QPS software is a useful method for predicting major cardiac events in patients with suspected cardiovascular disease (CVD). Predictive ability of TPD was similar to that of the semi-quantitative method with an expert interpreter's help. Moreover, this method can be helpful for CAD diagnosis and therapeutic evaluation of patients.

کلیدواژه ها:

Myocardial perfusion imaging ، Total perfusion deficits ، Quantitative perfusion SPECT software