Comparison of pretreatment and post-treatment whole body scan results (WBS) with I-۱۳۱ in ۹۴ patients with differentiated Thyroid cancer (DTC) [Persian]

Discrepancy between pre & post treatment WBSs (Low dose & high dose, respectively) is reported. The aim of this study was determination the post-treatment WBS role in the diagnosis of lesions not identified by the pretreatment one. In this study ۹۴ patients (pts) with DTC were evaluated. The results of pre & post treatment WBSs were compared. Overall, ۲۵.۶% of pts revealed more positive lisions in comparison with their pretreatment WBS. The increase in positive results in pts<۳۵ yr was ۳۶% and in pts>۳۵yr was ۲۵%. In males and females, the increased values were ۳۳.۳% & ۲۳.۵۸% respectively. In all types DTC post-treatment WBS revealed more involvement. In cases limited to thyroid, with capsular invasion and with lymph node involvement the increased values were: ۲۰.۵%, ۲۸.۵% & ۳۵.۷%, respectively. In cases with TSH<۳۰m U/L, ۵۳.۸% & in cases with TSH>۳۰ mU/L, ۲۲.۲% more positive lesions were observed. Pts with Htg<۱۰ ng/ml & >۱۰ ng/ml, post-treatment WBS revealed more lesions in ۲۸% & ۲۱.۸%, respectively. Conclusion: Post-treatment WBS improves rate of detection of thyroid cancer lesions. In our study this was especially true in cases with TSH<۳۰ mU/l & Pts younger than ۳۵yr.