Mucor Mycosis Associated with COVID-۱۹: A Case Series at a Tertiary Care Center in India.

سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 150

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شناسه ملی سند علمی:

JR_CJHR-7-2_001

تاریخ نمایه سازی: 1 تیر 1401

چکیده مقاله:

Background: COVID-۱۹ patients across the globe have been reporting several post-COVID health conditions such as respiratory, vascular, cardiac and renal complications and opportunistic infections; the most common of which has been fungal infections. Objective: The objective of our study was to identify socio-demographic characteristics, risk factors, clinical parameters, site of involvement and outcome of patients with COVID-۱۹ associated Mucor Mycosis (CAM) at a tertiary care centre in Rewa (Madhya Pradesh, India), Materials and Methods: This was a prospective observational study, conducted between ۱st May to ۳۰th June ۲۰۲۱; including ۴۰ patients who had Mucor Mycosis with recent or active COVID-۱۹. The data was collected using a structured data collection form by trained interviewers who were already working in Mucor Mycosis Ward. Results: The overall mean and median age of the patients was ۵۰.۸ years and ۵۲.۵ years respectively, with majority of the males (۷۲.۵%). Of total, ۴۷.۵% patients had active COVID-۱۹, whereas ۵۰% had recent COVID-۱۹ infection. Twenty-two patients (۵۵%) had co-morbidities, among whom the majority had underlying diabetes mellitus (۵۰%). History of Oxygen supplementation and use of steroids was found in ۷۵% and ۴۵% of the patients respectively. History of self-consumption of decoction (Kadha) and self-administration of inhalation drugs was found among ۲۲ (۸۰%) and ۸ (۲۰%) patients respectively. Twnty-one patients (۵۲.۵%) had gone through operative procedure/ intervention and ۱۱ (۲۷.۵%) patients received conservative treatment. In terms of outcome, ۲۰ patients (۵۰%) had been successfully discharged, followed by ۱۴ deaths (۳۵%), ۳ referrals (۷.۵%) to the higher centres and ۳ readmissions (۷.۵%). Conclusion: Addictions and Indian traditional therapies might have played crucial role in occurrence of CAM. In addition, although Oxygen supplementation and steroid consumption have been life-saving against COVID-۱۹, yet might be responsible for acute surge in CAM cases.  

نویسندگان

Charudatt Chalisgaonkar

Department of Ophthalmology, Shyam Shah Medical College associated with Sanjay Gandhi and Gandhi Memorial Hospital, Rewa, Madhya Pradesh, India

Sandeep Singh

Department of Community Medicine, Shyam Shah Medical College associated with Sanjay Gandhi and Gandhi Memorial Hospital, Rewa, Madhya Pradesh, India

Ambrish Mishra

Department of Community Medicine, Shyam Shah Medical College associated with Sanjay Gandhi and Gandhi Memorial Hospital, Rewa, Madhya Pradesh, India

Gaurav Derashri

Community Health Centre, Narwar, Ujjain, Madhya Pradesh, India.

Neera Marathe

Department of Community Medicine, Shyam Shah Medical College associated with Sanjay Gandhi and Gandhi Memorial Hospital, Rewa, Madhya Pradesh, India