Combination of compressed sensing-based iterative reconstruction and offset acquisition for I-۱۲۳ FP-CIT SPECT: a simulation study

سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 120

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شناسه ملی سند علمی:

JR_JNMB-10-2_005

تاریخ نمایه سازی: 21 خرداد 1401

چکیده مقاله:

Objective(s): The purpose of this study was to validate undersampled single-photon emission computed tomography (SPECT) imaging using a combination of compressed sensing (CS) iterative reconstruction (CS-IR) and offset acquisition.Methods: Three types of numerical phantoms were used to evaluate image quality and quantification derived from CS with offset acquisition. SPECT images were reconstructed using filtered back-projection (FBP), maximum likelihood-expectation maximization (ML-EM), CS-IR, and CS-IR with offset acquisition. The efficacy of CS-IR with offset acquisition was examined in terms of spatial resolution, aspect ratio (ASR), activity concentration linearity, contrast, percent coefficient of variation (%CV), and specific binding ratio (SBR).Results: The full widths at half maximum remained unchanged as the number of projections decreased in CS-IR with offset acquisition. Changes in ASRs and linearities of count density were observed for ML-EM and CS-IR from undersampled projections. The %CV obtained by CS-IR with offset acquisition was substantially lower than that obtained by ML-EM and CS-IR. There were no significant differences between the %CVs obtained from ۶۰ projections by CS-IR with offset acquisition and from ۱۲۰ projections by FBP. Although the SBRs for CS-IR with offset acquisition tended to be slightly lower than for FBP, the SBRs for CS-IR with offset acquisition did not change with the number of projections.Conclusions: CS-IR with offset acquisition can provide good image quality and quantification compared with a commonly used SPECT reconstruction method, especially from undersampled projection data. Our proposed method could shorten overall SPECT acquisition times, which would benefit patients and enable quantification with dynamic SPECT acquisitions.

نویسندگان

Norikazu Matsutomo

Department of Medical Radiological Technology, Faculty of Health Sciences, Kyorin University, Tokyo, Japan

Takeyuki Hashimoto

Department of Medical Radiological Technology, Faculty of Health Sciences, Kyorin University, Tokyo, Japan

Mistuha Fukami

Department of Medical Radiological Technology, Faculty of Health Sciences, Kyorin University, Tokyo, Japan

Tomoaki Yamamoto

Department of Medical Radiological Technology, Faculty of Health Sciences, Kyorin University, Tokyo, Japan

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