A Six-Month Survey of the Frequency of Extensively Drug-resistant Gram-Negative Bacteria by VITEK ۲ System in ۲۰۲۰
سال انتشار: 1400
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 174
فایل این مقاله در 7 صفحه با فرمت PDF قابل دریافت می باشد
- صدور گواهی نمایه سازی
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_IJMM-16-2_005
تاریخ نمایه سازی: 28 فروردین 1401
چکیده مقاله:
Background and Objective: Increasing of resistant bacteria is a major concern globally. The emergence of XDR gram-negative bacteria is a more serious problem due to treatment limitations. This study aimed to evaluate the frequency of extensively drug-resistant (XDR) gram-negative bacterial isolates in different clinical samples from Payvand Clinical and Specialty Laboratory, Tehran, Iran, for ۶ months by VITEK ۲ system.
Materials and Methods: During March ۲۰۲۰-September ۲۰۲۰, different clinical samples were collected from patients referred to Payvand Clinical and Specialty Laboratory. Bacterial identification and antimicrobial susceptibility test (AST) were performed applying an automated VITEK ۲ system. The frequency of identified bacteria, their resistance to common antibiotics and also XDR bacteria were calculated and reported, respectively.
Results: Overall, ۴۱۲۵ urine specimens, ۳۴ sputum samples, and ۱ tracheal aspirate tube were submitted to Payvand Laboratory during ۶ months. Of them, ۴۸۶ urine, ۳۲ sputum, and a tracheal aspirate tube samples were culture positive. Gram-negative isolated bacteria were included in this study. Based on AST, ۶۳.۳% of the isolated Klebsiella pneumoniae, ۱۰۰% of Pseudomonas aeruginosa, and all Acinetobacter baumannii isolates were susceptible to amikacin and colistin. Totally, ۳۱ XDR gram-negative bacteria, including: K. pneumonia (ssp. pneumonia (n=۲۰), and ozaenae (n=۲), Escherichia coli (n=۳), P. aeruginosa (n=۵), and A. baumannii (n=۱) were identified from ۱۸ urine samples, ۱۲ sputum specimens, and a tracheal aspirate tube.
Conclusion: The rate of XDR bacteria was high in the investigated laboratory in this study. Therefore, accurate screening and antimicrobial stewardship is recommended in different medical centers of Iran.
کلیدواژه ها:
Automation ، Drug resistance ، Gram negative bacteria ، antibiotics ، اتوماسیون ، مقاومت دارویی ، باکتری های گرم منفی ، آنتی بیوتیک ها
نویسندگان
Sepideh Ghasemshahi
Department of Microbiology, Payvand Clinical and Specialty Laboratory, Tehran, Iran
Mohammad Ahmadpor
Department of Microbiology, Payvand Clinical and Specialty Laboratory, Tehran, Iran
Azam Booskabadi
Department of Microbiology, Payvand Clinical and Specialty Laboratory, Tehran, Iran
Hadi Rezaei
Department of Microbiology, Payvand Clinical and Specialty Laboratory, Tehran, Iran
Behzad Poopak
Head of Payvand Clinical and Specialty Laboratory, Tehran, Iran
Mojdeh Hakemi-Vala
Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences (SBMU), Tehran, Iran
مراجع و منابع این مقاله:
لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :