The Effect of Topical Oxygen Therapy on Diabetic Foot Ulcer

Background and Obgective:Diabetic foot ulcer is a serious complication and if left untreated, it can cause irreparable problems for the patient. The present study was determine the effect of topical oxygen therapy on the healing of diabetic foot ulcers.Materials and Methods:In this one-blind and multicenter randomized clinical trial, ۴۰ patients admitted to Qazvin Educational and Medical Centers in ۱۳۹۸ were randomly assigned using coin toss and block randomization in one They were divided into two groups of control and test (۲۰ people in each group). In the control group, the only daily care that included routine cares was performed by washing the wound with normal saline and then with dry sterile gauze and with conventional dressing products twice a day.In the experimental group, in addition to the above care, topical oxygen therapy with direct use of high pressure dry oxygen by oxygen catheter at a distance of one centimeter from the wound, with a flow of ۱۰ liters per minute for ۲۰ minutes, three times a day for at least one It was the week. The present study has the code of ethics IR.QUMS.REC.۱۳۹۷.۳۹۵ and more ethical considerations are available on the IRCT website (registration number:IRCT۲۰۱۹۰۷۰۸۰۴۴۱۴۸N۱).Findings:. The results of analysis of variance showed that only the interaction of the two variables of height and total wound score was significant with time (P = ۰.۰۰۱ for height and P <۰.۰۰۱ for total score, respectively). Benfroni post hoc test showed that the depth and total score of the wound in the intervention group had a significantly stronger downward trend than the control group.Conclusion:Topical oxygen therapy had no significant effect on wound size, but the depth and score of the whole wound was significant. Extensive studies with longer intervals are recommended.

کلیدواژه ها:

oxygen ، topical oxygen therapy ، ulcers ، diabetic foot ulcers