Chlorpromazine-HCl Determination via Its Oxidation with Sodium Nitrite in Sulfanilic Acid Medium via CFIA Technique through Long Distance Chasing Photometer NAG-ADF-۳۰۰-۲

In this work, precipitation reaction with a new photometer NAG-ADF-۳۰۰-۲ analyzer was used to detect chlorpromazine hydrochloride by attenuation of incident light (White Snow Light Emitting Diode) at two steps, the first ۱۱۰ mm and the second ۶۰ mm with a separation distance of ۱۰۰ mm of the chlorpromazine-hydrochloride reaction with a mixture of two reagents of sodium nitrite and sulfanilic acid form a yellowish-white precipitate. The attenuation of this precipitate by incident light was measured in a highly repeatable and reproducible way from a relative standard deviation percent (RSD %) of less than ۰.۳% at a variable concentration. The linear dynamic graph ranges from ۰.۵ to ۴۵ mmol.L-۱ for Cell A and ۱-۴۳ mmol.L-۱ for Cell B, with a limit of detection (L.O.D) ۰.۹۹۸۴ μg and ۴۹.۹۲۳۹ μg at ۲۸۱ μL sample, and a correlation coefficient (r) of ۰.۹۹۹۴, ۰.۹۹۹۳ for Cell A and Cell B, respectively

کلیدواژه ها:

Chlorpromazine-HCL ، Flow injection analysis ، NAG-ADF-۳۰۰-۲ photometer ، sulfanilic acid