The Effect of Pimecrolimus Cream ۱% Compared with Triamcinolone Acetonide Paste in Treatment of Atrophic-Erosive Oral Lichen Planus

سال انتشار: 1394
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 139

فایل این مقاله در 8 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:

شناسه ملی سند علمی:

JR_IJOTO-27-2_006

تاریخ نمایه سازی: 11 بهمن 1400

چکیده مقاله:

Introduction: Oral lichen planus (OLP) is a common chronic mucocutaneous disease. Patients with atrophic and erosive types of OLP often have symptoms of soreness, and require proper treatment. The main treatment for OLP has been the administration of topical or systemic corticosteroids. The objective of this study was to compare the efficacy of adcortyl cream (triamcinolone acetonide in orabase) with topical pimecrolimus cream for the treatment of erosive OLP.   Materials and Methods: Twenty-eight patients with OLP were enrolled in a single blind clinical trial and assigned to either a pimecrolimus ۱% cream group or an adcortyl ۰.۱% cream group. The medication was applied every day for ۲ months and patients were assessed every ۲ weeks.   Results: The mean lesion size and mean pain and burning sensation scores did not differ between the pimecrolimus and adcortyl cream groups. The pimecrolimus cream was well tolerated. No clinical drug-related adverse events were observed.   Conclusion:  Topical pimecrolimus cream may be recommended as a safe and effective alternative therapy in the treatment of OLP. Pimecrolimus cream is as effective as adcortyl cream in managing the signs and symptoms of OLP.

نویسندگان

Atessa Pakfetrat

Oral and Maxillofacial Diseases Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.

Zahra Delavarian

Oral and Maxillofacial Diseases Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.

Farnaz Falaki

Oral Medicine Specialist, DDS MSc, San Diego, USA.

Mahboubeh Khorashadizadeh

Department of Oral Medicine, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.

Mina Saba

Dentist, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.

مراجع و منابع این مقاله:

لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :
  • Axéll T, Zain RB, Siwamogstham P, Tantiniran D, Thampipit J. Prevalence of oral soft ...
  • Bánóczy J, Rigó O. Prevalence study of oral precancerous lesions within ...
  • Eisen D. The clinical features, malignant potential, and systemic associations of oral lichen planus: a study of ۷۲۳ patients. J Am Acad Dermatol. ۲۰۰۲; ...
  • Greenburg MS, Glick M, Ship JA. Burket's oral medicine.۱۱th ed. Hamilton: BC Decker Inc; ۲۰۰۸. p. ۸۹-۹۵ ...
  • Volz T, Caroli U, Lüdtke H, Bräutigam M, Kohler-Späth H, Röcken M, et al. Pimecrolimus cream ...
  • Silverman S Jr, Gorsky M, Lozada-Nur F. A prospective follow-up study of ...
  • Shen ZY, Liu W, Zhu LK, Feng JQ, Tang GY, Zhou ZT. A retrospective clinicopathological ...
  • Radfar L, Wild RC, Suresh L. A comparative treatment study ...
  • McCaughey C, Machan M, Bennett R, Zone JJ, Hull CM. Pimecrolimus ۱% cream for ...
  • Lodi G, Carrozzo M, Furness S, Thongprasom K. Interventions for treating oral lichen ...
  • Azizi A, Lawaf S. The comparison of efficacy of adcortyl ointment ...
  • Ruzicka T, Assmann T, Homey B. Tacrolimus: the drug for the turn ...
  • Laeijendecker R, Tank B, Dekker SK, Neumann HA. A comparison of treatment of ...
  • Shichinohe R, Shibaki A, Nishie W, Tateishi Y, Shimizu H. Successful treatment of severe ...
  • Thongprasom K, Luangjarmekorn L, Sererat T, Taweesap W. Relative efficacy of fluocinolone acetonide ...
  • Scully C, Eisen D, Carrozzo M.Management of oral lichen planus. Am J ...
  • Becker JC, Houben R, Vetter CS, Bröcker EB. The carcinogenic potential of tacrolimus ...
  • Mattsson U, Magnusson B, Jontell M. Squamous cell carcinoma in a patient ...
  • Passeron T, Lacour JP, Fontas E, Ortonne JP. Treatment of ...
  • Swift JC, Rees TD, Plemons JM, Hallmon WW, Wright JC. The effectiveness of ۱% pimecrolimus cream in the ...
  • Gorouhi F, Solhpour A, Beitollahi JM, Afshar S, Davari P, ...
  • نمایش کامل مراجع