Experimental study and thermodynamic modeling of mesalamine solubility in deep eutectic solvents (DESs)

سال انتشار: 1400
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 229

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شناسه ملی سند علمی:

NICEC17_276

تاریخ نمایه سازی: 27 دی 1400

چکیده مقاله:

The solubility of mesalamine in some choline chloride (ChCl) and N, N-diethyl ethanol ammonium chloride (DEAC) based DESs with ethylene glycol and propanediol was measured within the temperature range of ۲۸۳.۱۵ to ۳۲۳.۱۵ K. The results showed that the solubility was enhanced by increasing the temperature and increased to ۱۵-۳۰ fold in DESs rather than water. The experimental solubility data were accurately correlated using the local composition models such as Wilson and NRTL. Moreover, the two temperature-dependent Buchowski-Ksiazaczak λh and modified Apelblat equations were applied to correlate the present data.

نویسندگان

t amini

Process Engineering Group, Faculty of Chemical Engineering, Tarbiat Modares University, P.O. Box ۱۴۱۱۵-۱۴۳, Tehran, Iran

a haghtalab

Process Engineering Group, Faculty of Chemical Engineering, Tarbiat Modares University, P.O. Box ۱۴۱۱۵-۱۴۳, Tehran, Iran

j yousefi seif

Department of Chemical Engineering, Hamedan University of Technology, P.O. Box ۶۵۱۵۵-۵۷۹, Hamedan,Iran