In vestigatio n of Inter action between Nanotubes and Anti-Ca ncer Drugs

Cycloxan is used to treat various types of cancer a nd some a utoimmune disorders. It is a "prodr ug"; it is converted in the liver to active forms that have ch emotherape utic activity . The main use of Cy cloxan is t ogether with other ch emotherapy agents in the treatment of lymphomas, some forms of brain ca ncer, leukemia and s ome solid tumors. It is a chemo therapy drug that works by slowin g or stopping cell growth. Ifosfamid e, like Cycloxan, is an oxazophosphorine al kylating agent.Followin g activatio n in the liver, ifosf amide interfe res with DN A through formation of phosphotriesters and DNA-DNA crosslinks, thereby inhibiting protein synthesis and DNA synthesis. In this wo rk the int eraction bet ween Nanotubes and th ESE anti-C ANCER dru g is investigated to show if the Nanotubes are safe to deliver this drug.

کلیدواژه ها:

Nano tube ، Cyclox an ، Ifosfamide ، DFT ، NBO.