Design an d Measure ment of novel Nanotube(۶,۶) and Cali x[n]arene derivatives Therm odynamic Functio n as drug delivery by DFT

Calixa renes are a group of organic macrocyclic agents that have cup like sha pe which a re easily available through the cyclocondensation of para-substituted phenols with formaldehyde. One way t o increase t he aqueous solubility of drugs is to use complexing agents to form ha st- guest complexes [۱-۲]. Single-walled carbon nanotube ( SWCNTs) is allotropes of carbon with a cylindrical nanostructure. Th e covalent attachment of chemical group to SWCNTs is very promising for the applications of drug delivery and gas sensing properties [۳, ۴]. Calixarenes are promising materials for nan omedicine application in drug delivery systems. For example hydrophilic derivatives have shown in teresting le vels of activity agai nst bacteria, fungi, cance rous cells a nd enveloped viruses, b ut also against thromb osis or fibro sic disease s. These applications can be obtained from Natotu bes, too. Be cause of the safe delivery of drugs i n human body, in this pa per ability of Calixarenes and Na notube in transporting skin anticancer is compa red.

کلیدواژه ها:

Calix arene ، Drug delivery ، Nanotube ، An ticancer ، D FT.