Kinetic study of reactive oxygen sp ecies pro duction u pon photoexcitation of sun care agents suc h as TiO۲, ZnO an d ZrO۲

Reactive oxygen species (ROS) are free radicals that continuously produced thr ough a variety of normal m etabolic pr ocesses.[۱]R eactive oxygen species, include sin glet oxygen , superoxide and hydroxyl radicals, a nd hydrogen peroxide.[۲]The unco ntrolled production of ROS may lead to inflamma tion, aging, neurodegenerative disorders and cancer. Many sunscreens contain light-reflective agents su ch as TiO۲, ZnO and ZrO۲,to achieve high SPF(Sun Protection Factor) ratings.TiO۲, ZnO a nd ZrO۲hav e been repo rted to be an effective photocatalyst agent, which is able to generate reactive ox ygen speci es.[۳] In u ric acid(UA) assay TiO۲, ZnO and ZrO۲irra diated, UA o xidize by pr oduced ROS by inorga nic oxides.Purpose of this paper is identific ation of kinetic mechanism of ROS production b y irradiatio n of TiO۲, ZnO and ZrO۲ by using kinetic Monte Carlo simula tion.

کلیدواژه ها:

Reactiv e oxygen sp ecies ، Kinetic Monte Carlo ، Inorganic oxides ، simulation.