Theoretical study on the mechanism of the reaction of ۱, ۵ enynes having a Si atom with nucleophiles catalyzed by Gold complexes

Gold (I) complex es are capable catalysts for activating enynes towards reaction with alc ohols. For E xample, the experimenta l data’s Toste showed that the reaction of ۱, ۵ enynes containing a silicon atom at the ۳-position (see I) with alcohols in presence of Au (I) complexes, the products II and III are formed. In such a case Toste investigated that, depending on nature of heteronucleophiles, different products are formed. When the heteronucleophile is PhOH, product II is form ed and when the hetero nucleophie is MeOH product III is formed (scheme ۱). [۱]

کلیدواژه ها:

Gold ، Enyne ، Silicon atom ، Alcohol