Physicoch emical evaluation of Microemulsion fo rmulations for Water+Ipm+Tween ۸۰+Isobutanol Pseudo-ternary System

Microem ulsions are clear, thermodynamically stable solution mixtures of at least thr ee compone nts, namely , two immiscible solv ents and a surfactant. The three basic types of Microem ulsions are direct (oil dispersed in water, o/w), reversed (water dispers ed in oil, w/o) and bico ntinuous structure [۱]. The Mic roemulsion region is usually characterized b y construct ing ternary-phase diagrams . To constru ct a pha rmaceutically accepte d Microem ulsion system it is im portant to know its physicochem icalproper ties. For t he selection of compo nents of a biocompatib le Microem ulsion system, The ch anges in t he internal structure of a Microemu lsion can be monitored by analyzi ng some ph ysicochemical properties such as co nductivity, viscosity, density, PH, Refractive Index [۲]. T he aim of this study is Physicochem ical evaluation of Microemulsion formulations.

کلیدواژه ها:

Microe mulsion ، Pseudo-ternary ، phase diagram ، Physicochemical properties