The physiological and pharmacological effects of Ziziphoratenuior L.: A review study

سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 330

فایل این مقاله در 14 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:

شناسه ملی سند علمی:

JR_AJP-12-1_003

تاریخ نمایه سازی: 27 آذر 1400

چکیده مقاله:

Objective: Many reports have revealed preventive and therapeutic effects of Ziziphoratenuior; however, few systematic reviews have evaluated such effects. The present study reviews the physiological and pharmacological effects of Z. tenuior extract and its components.Materials and Methods: English articles were searched in international databases, such as Embase, Scopus, and PubMed; Persian studies were also searched in national databases such as SID and Magiran.Results: Pulegone is one of the most important effective compounds of Z. tenuior, which has analgesic, anti-inflammatory, and anti-stress properties as it affects serotonergic and opioidergic systems and decreases the gastric acid secretion. Moreover, this compound inhibits cholesterol absorption and synthesis, resulting in hyperlipidemic effects and weight loss. In addition to its antioxidant, antitumor, and antibacterial properties, this herb contains an antidiabetic effect mediated by increasing the number of pancreatic beta cells and insulin secretion, and inhibiting alpha-amylase. Although its effective dosage has no side effects, the overuse of its effective compounds, such as pulegone, may raise some liver and pulmonary disorders.Conclusion: Z. tenuior and its extract can have preventive and therapeutic effects on diabetes and hyperlipidemia-associated diseases. Since most studies on this herb were in vivo, it is necessary to design clinical trials to evaluate its effects.

کلیدواژه ها:

نویسندگان

Ali Zarei

Department of Physiology, Estahban School of Paramedical Sciences, School of Nursing Hazrat Zahra (P.B.U.H) Abadeh, Shiraz University of Medical Sciences, Shiraz, Iran

Saeed Changizi-Ashtiyani

Department of Physiology, Arak University of Medical Sciences, Arak, Iran

Behnam Masmouei

Department of Nursing, School of Nursing Hazrat Zahra (P.B.U.H) Abadeh, Shiraz University of Medical Sciences, Shiraz, Iran

Fatemeh Rasekh

Department of Biology, Payam Noor University of Tehran, Tehran, Iran

Mansour Sokhandani

Department of Nursing, School of Nursing Hazrat Zahra (P.B.U.H) Abadeh, Shiraz University of Medical Sciences, Shiraz, Iran

Fridoon Jahangir

Department of Nursing, School of Nursing Hazrat Zahra (P.B.U.H) Abadeh, Shiraz University of Medical Sciences, Shiraz, Iran