One-Pot synthesis of ۲-amino-۴H-chromenes using L-Prolineas a reusable catalyst

A new and efficient synthesis of۲-amino-chromenes is achieved by one pot three-component reaction of aldehydes, malononitrile, and resorcinol using L-proline as a reusable catalyst.The key advantages of the present process are the use of a bioorganic and reusable catalyst, high yields of products, using green solvent and short reaction times from the principles of green chemistry point of view.

کلیدواژه ها:

۲-amino-chromenes ، Three-component reaction ، L-proline ، Reusable catalyst ، Green solvent