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مقالات فارسیISIکنفرانسهاژورنالها

The Extract of Crocus sativus and Its Constituent Safranal, Affect Serum Levels of Endothelin and Total Protein in Sensitized Guinea Pigs

محل انتشار: مجله علوم پایه پزشکی ایران، دوره: 16، شماره: 9
سال انتشار: 1392
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 362

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لینک ثابت به این مقاله:
https://civilica.com/doc/1297969

شناسه ملی سند علمی:

JR_IJBMS-16-9_012

تاریخ نمایه سازی: 4 آبان 1400

چکیده مقاله:

  Objective(s): The effect of the extract of Crocus sativus and its constituent, safranal on inflammatory markers in sensitized guinea pigs was examined.   Materials and Methods: Ovalbumin (OA) sensitized guinea pigs were given drinking water alone (group S), or drinking water containing three concentrations of safranal, three concentrations of extract and one concentration of dexamethasone, (n=۶, for all groups) and serum levels of endotheline-۱ (ET-۱) and total protein (TP) were assessed. Results: Serum levels of ET-۱ and TP in group S were significantly higher than control group (P Conclusion: A preventive effect of the extract of C. sativus and its constituent safranal on serum inflammatory markers in sensitized guinea pigs was shown.

کلیدواژه ها:

Asthma Crocus sativus Endotheline Inflammation Safranal Sensitization

نویسندگان

Zahra Gholamnezhad

Applied Physiology Research Centre, and Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Hamed Koushyar

Applied Physiology Research Centre, and Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Goltaj Byrami

Applied Physiology Research Centre, and Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Mohammad Hossein Boskabady

Applied Physiology Research Centre, and Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

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