A review article: bacterial strain and antibiotic resistant pattern in burn wound

Background and Aim : Microbial infection is the most common and serious complication of burn injury, which is a major cause of morbidity and mortality. Burn infections are one of the most common serious illnesses caused by pathogens, mainly by both gram-negative and gram-positive bacteria. The aim of this study was to determine the bacteriological stains and the antibiotic resistance patterns in Burn wound Methods : We carried out a systematic search on the bacterial stain and antibiotic resistant pattern of burn wound infections in the world using different electronic databases including Embase, Scopus, Web of Sciences, PubMed/Medline, during ۲۰۰۵ to ۲۰۲۰. These databases were explored to find out potentially relevant pieces of literature. Keywords were used was the prevalence, bacterial isolates, burn wound antibiotic resistance.Results : Our study included ۳۱ data report of comprising ۱۵۸۵۵ patients sample (female and male), with about ۵۵۰۰ total positive cultures from different countries. Various Gram negative bacteria Pseudomonas aeruginosa, Klebsiella pneumoniae, Proteus spp, Escherichia coli and Gram positive bacteria including Staphylococcus spp especially S.aureus (MSSA, MRSA), S. epidermidis, Coagulase-Negative Staphylococci (CoNS), Streptococcus spp. The obtained results showed that P. aeruginosa demonstrated resistance to ciprofloxacin ۹۴%, Amikacin ۸۸%, gentamicin ۸۲%, imipenem ۷۰% and ceftazidime ۶۴%. Also, S.aureus demonstrated similar trends with resistance to ciprofloxacin ۸۰%, Amikacin ۶۰% , gentamicin ۶۰%. Conclusion : Due to various reasons, including the indiscriminate use of antibiotics, especially in recent years, the resistance of bacteria to antibiotics is increasing. As shown in different studies, bacteria, especially gram-negative ones, are MDR and resistant to different antibiotics, which is one of the serious challenges in treating wound infections.

کلیدواژه ها:

bacterial strain ، wound infection ، antibiotics resistance ، world