Bacterial Infections and Antimicrobial Resistance Patterns of Burn Wound Infections: A One Year Study from Burn Hospital, Isfahan, Iran

Background and Aim : The development of infections in burn wound is serious because of their effects on the course of the disease and the patient outcomes. The rate of infection in burn cases is extremely high in developing country. The aims of this study were to identify the common bacterial agents responsible for burn wound infection and determine antimicrobial susceptibility patterns in burn Hospital, Isfahan, Iran.Methods : This cross sectional study was conducted at one year period for all patient with burn wound infection. Burn wounds suspected of infection were collected aseptically and conventional bacteriological methods were followed for identification of the bacteria. Antimicrobial susceptibility tests were performed by using the disk diffusion method in accordance with CLSI recommendations. Results : from the total of ۱۵۰۰ wound culture, ۹۵۷(۶۳.۸%) samples were detectd positive. The highest rate of infection was in the ICU ward and the lowest was in the restoration ward. The most common gram negative bacterias were Acinetobacter baumannii (۳۴.۹%) with the highest and the lowest antibiotic resistance to Ceftazidime and Tobramycin. Among recovered Gram positive isolates, Staphylococcus aureus (۱۰.۲%) were the predominant isolates with the highest and the lowest antibiotic resistance to Penicillin and Vancomycin. Conclusion : : Due to the variable nature of antibiotic susceptibility patterns and pathogens causing burn wound infection, continuous evaluation and detection of dominant bacterial infections and sensitivity patterns to locally available antibiotics in burn wound patients in order to modify the drug regimen for Proper antibiotic treatment is important and seems reasonable.

کلیدواژه ها:

bacterial infection ، burn patients ، antimicrobial resistance pattern