Identification and characterization of Staphylococcus aureus isolated from Imam Reza hospital, Kermanshah

Background and Aim : Staphylococcus aureus (S. aureus) almost can cause disease in all organs such as osteomyelitis, pneumonia, sepsis, and superficial skin infection. S. aureus through many factors include toxin, cell wall-associated proteins, and protein modulators can resist immune response. S. aureus can be categorized into two types based on resistance to the Methicillin, Methicillin-resistance Staphylococcus aureus (MRSA) and Methicillin-sensitive Staphylococcus aureus (MSSA). Methods : ۹۵ isolates were collected from November ۲۰۲۰ to June ۲۰۲۱. Differentiation of these two types is done through the presence of mec gene. In the next step antibiotic resistance is done through Kirby-Bauer Method on the Muller-Hinton agar. Results : among ۹۵ isolates, ۶۵ number were identifying as MRSA, and ۳۰ isolate as MSSA. The highest level of resistance among the studied antibiotics was related to Cefoxitin. Other antibiotics that investigated in this study include Oxacillin and Cefotaxime.Conclusion : most of the isolates are MRSA that concludes that the percent of bacteria that carrier the antibiotic resistance are in progress. Abusing of medication of course is one of the major roles in this enhancement.

کلیدواژه ها:

Staphylococcus aureus ، antibiotic resistance ، MRSA ، Oxacillin