Evaluation of Antibiotic Resistance in Isolates from UTI in Department of Pediatrics, Shohada Hospital, Izeh, in Khuzestan province

Background and Aim : One of the most important infections in children is urinary tract infection. It is essential to prevent serious complications of urinary tract infections in children, such as high blood pressure and kidney failure, and definitive diagnosis and immediate treatment is needed. Since the Enterobacteriaceae family is the most common cause of urinary tract infection, the aim of this study was to evaluate the antibiotic resistance in isolates from the UTI in department of pediatrics in Shohada hospital at Izeh in ۲۰۱۷. Methods : This cross-sectional study was performed on urine specimens of children with UTI who were admitted to the pediatric ward of Shohada hospital at Izeh during ۳ months (from April to June). Urine specimens were cultured on selected media and isolates were identified by biochemical tests. Antibiotic resistance pattern was studied by disk diffusion.Results : From ۱۱۰ urine samples related to the children admitted to the pediatric ward of Shohada Hospital at Izeh, ۵۳ were female (۴۸/۲) and ۵۷ were male (۵۱/۸). Escherichia coli with ۱۵/۵% outbreak, was the most prevalent bacterium isolated among Enterobacteriaceae family. Clinical isolates were most susceptible to amikacin (۷۶/۴%) and imipenem (۶۴/۷%) and had the highest resistance to ceftriaxone (۱۰۰%).Conclusion : Considering the prevalence of urinary tract infections in children, for preventing its serious complications, evaluation of regional pattern and timely treatment must be done. For experimental treatment of urinary tract infections in children, amikacin and imipenem antibiotics are recommended.

کلیدواژه ها:

UTI ، Pediatrics ، Escherichia Coli ، Antibiotic Resistance ، Diffusion Disc