Frequency and antibiotic susceptibility of non-fermenting Gram-negative bacteria isolated from hospitalized patients in Hazrat Zeinab hospital, ۲۰۱۶-۲۰۱۷.

Background and Aim : Antimicrobial resistance to the available antibiotics has been emerged as a serious problem in treatment worldwide which causes high rates of morbidity and mortality. The aim of this study was to investigate the frequency and antibiotic resistance patterns of non-fermenting Gram-negative bacteria including Acinetobacter baumannii and Pseudomonas aeruginosa. Methods : This was a cross-sectional study that was conducted in a referral hospital, by using a questionnaire including patients’ age, gender, and the sampling site, severity of bacterial growth, type of organism which was found on the medium, and also the result of antibiogram tests.Results : Of ۲۱۰ patients including (۷ adults and ۲۰۳ neonates) were evaluated in this study. The most prevalent resistance of Acinetobacter baumannii was related to amikacin (۸۹.۴%), ceftazidime (۸۶.۵%), gentamicin (۷۰%), imipenem (۷۰.۹%),cefepime ( ۶۷.۴%), ciprofloxacin (۶۰.۳%),cotrimoxazole (۳۶.۲%), tetracycline( ۹.۹%), and cefotaxime (۵.۷%). Also,the most resistance frequency of P.aeroginosa was associated were these antibiotics: amikacin (۳۱.۹%), gentamicin (۳۱.۹%), ceftazidime (۲۹%), cefepime (۲۴.۶%), ciprofloxacin (۱۱.۶%), and imipenem( ۱۰.۱%).Conclusion : It was concluded that the lowest rate of resistance was associated with tetracycline in A.baumannii, however, the lowest resistance rate of P.aeroginosa was associated with ciprofloxacin and imipenem.

کلیدواژه ها:

Acinetobacter baumannii ، pseudomonas aeruginosa ، neonate ، antibacterial resistance ، Iran.