Evaluation of the antioxidant and antibacterial effect of Inula aspera various extracts

سال انتشار: 1400
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 142

نسخه کامل این مقاله ارائه نشده است و در دسترس نمی باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:

شناسه ملی سند علمی:

MEDISM22_011

تاریخ نمایه سازی: 8 مهر 1400

چکیده مقاله:

Background and Aim : Inula aspera, belongs to Asteraceae family, is a perennial medicinal herb native to Asia and southeastern Europe. The aim of this study was to investigate the antioxidant and antibacterial activities of Inula aspera various extracts. Methods : Inula aspera plants were collected from North Khorasan Province, Iran and dried in shade. The aerial parts of I. aspera were extracted using various solvent systems, including water, methanol, and hexane. Antioxidant activity of the plant extracts was measured using ۱,۱-diphenyl-۲-picrylhydrazyl (DPPH) spectrophotometry. The microdilution technique was used to evaluate the antibacterial assay and minimum inhibitory concentration (MIC) against four potential pathogenic bacteria strains including Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Enterococcus faecalis.Results : According to the preliminary findings of this study, aqueous extract of I. aspera in comparison to the other extracts, had the highest antioxidant activity. IC۵۰ values of aqueous, methanol, and n-hexane extracts were found to be ۴۱۶.۴۱, ۶۶۱.۰۲ and ۱۴۶۴ µg/ml. Aqueous and methanol extracts demonstrated significant antibacterial activity against all tested bacterial strains, with MIC values ranging from ۲۵ to ۱۰۰ mg/mL. The most sensitive strain was E. coli (MIC= ۲۵ mg/ml), and the most resistant strain was P. aeruginosa (MIC= ۱۰۰ mg/ml).Conclusion : The results of this study showed that I. aspera can be considered as a potential source of a natural antioxidant and antibacterial product in food, medicine and cosmetic industries.

کلیدواژه ها:

نویسندگان

Vajihe Hashemi

Department of Biology, Kavian inestitute Higher Education Institute, Mashhad, Iran.

nazanin ataee

Department of Biology, Kavian Higher inestitute Education Institute, Mashhad, Iran.

samaneh attaran

Department of Biology, Faculty of Sciences, Ferdowsi University of Mashhad, Mashhad, Iran