Photonic crystal based on porous silicon as a biosensor
سال انتشار: 1400
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 311
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شناسه ملی سند علمی:
ICNNA02_248
تاریخ نمایه سازی: 4 مهر 1400
چکیده مقاله:
One-dimensional photonic crystals were fabricated based on porous silicon (PSi) by electrochemical method. These nanostructures consisted of ۲۰ alternating porous layers of low and high porosity. Low porosity (L) layers (high refractive index) have ۶۲% ± ۵% porosity, ۹۰ nm ± ۱۱ nm thickness and refractive index of ۱.۵۰ ± ۰.۱۴. However, these parameters for high porosity (H) layers (low refractive index) are ۷۵% ± ۳%, ۱۲۵ nm ± ۱۰ nm and ۱.۴۶ ± ۰.۰۷ respectively. To detect human growth hormone (hGH), the photonic crystal surface was oxidized, modified by APTES ((۳- Aminopropyl) triethoxysilane), glutaraldehyde (GA) as biochemical linkers, and then anti-growth hormone antibody (anti-hGH) as biorecepotor. Linear response to hGH inthe range of ۱۰۰ ng/ml-۵۰۰ ng/ml in PBS buffer was obtained.
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نویسندگان
Fereshteh Rahimi
Dr. , Division of Nanobiotechnoloy, Department of Life Science Engineering, Faculty of New Sciences and Technologies, University of Tehran, Tehran, Iran,
Behnam Yarani
Mr., Division of Nanobiotechnoloy, Department of Life Science Engineering, Faculty of New Sciences and Technologies, University of Tehran, Tehran, Iran
Fatemeh Razi Astaraei
Dr., Renewable Energies and Environmental Department, Faculty of New Science and Technologies, University of Tehran, Tehran, Iran