Preparation of novel nano solid base catalysts and their application in synthesis of chalcones

With attention to the imprtance of nano technology in various field such as: industrial, pharmacetical and organic synthesis, in this research, initially, nano clinoptilolite (NCP), preparated using green method. The nano structure of preparated NCP confirmed by X-ray diffraction and scaning electron microscopy. In the next step, surface of NCP modified by reaction of synthetic nano clinoptilolite with chloropropyltrimethoxysilan and HMTA at room temprature conditions. The synthesized functionallized nano clinoptilolite (NCP@HMTA) characterized using various technicques such as; FT-IR, X-ray diffraction, scaning electron microscopy and energy-dispersive X-ray spectroscopy. With attention to the importance of compounds contaning indandione due to their application in industrial and pharmacetical, in continuation of our research, catalytic activity of synthetic NCP@HMTA studied for preparation of chalcon drivatives. For this mind, raction of indanedion (1mmol) with variouse aldehydes (1mmol) in the presence of nano solid base catalyst NCP@HMTA has been investigated in EtOH as a solvent. With attention to obtained results, desire products have been prepared in excellent yields and short reaction times, without any byproduct, in the presence of nano clinoptilolite solid base catalyst. In the absence of this nano catalyst, no product was observed after long reaction times. The structure of synthetic products characterized using FT-IR, 1 H NMR, 13 C NMR and Mass spectromeric data

کلیدواژه های Preparation of novel nano solid base catalysts and their application in synthesis of chalcones:

NCP@HMTA ، Synthesis ، Characterization ، Chalcone ، Nano Catalyst.