Pseudomonas aeruginosa isolates and their antimicrobial susceptibility pattern to SXT and IPM between hospitalized patients at Urmia University Teaching Hospital, Iran

Background and Aim : Pseudomonas aeruginosa considered as prevalent bacterial pathogen with high distribution in health care settings. Regardless of progress in medical cares, Pseudomonas aeruginosa remains a cause of infection. Therefore, this study aims to isolate and determine antimicrobial susceptibility patterns of Pseudomonas aeruginosa from Patients admitted to educational hospitals at the Urmia University of Medical Sciences, Iran.Methods : Body fluids and aspirate specimens hospitalized patients were collected. The samples were inoculated on MaConckey and blood agar plates, and incubated at ۳۷ °C for ۲۴ h. The isolates were recognized with conventional microbiological tests. Antimicrobial susceptibility pattern was detected by modified Kirby-Bauer disk diffusion test.Results : From total examined cases, ۱۰۰ specimens have Pseudomonas aeruginosa positive cultures. The high rate of collected Pseudomonas aeruginosa was isolated from urine samples (۶۲ %) followed by sputum, wound and tracheal aspirates respectively. Major Pseudomonas aeruginosa isolates were found to be susceptible to IPM and most isolates were resistant to SXT.Conclusion : The result shows higher prevalence of Pseudomonas aeruginosa isolates among urine samples. the isolates were more susceptible to the IPM in compared to SXT. While the susceptibility of the isolates to the two examined antibiotics is a valuable data for the their future usage in infection management strategies.

کلیدواژه ها:

urine ، antibioyic ، Body fluids ، antibiotic resistance pattern