The Effect of Kelussia odoratissima on Pathogenic Bacteria in Enterobacteriaceae Family

Background and Aim : Kelussia odoratissima is one of the native plants of Iran and Enterobacteriaceae is a large family of Gram-negative bacteria. The aim of this study was to determine the antibacterial effect of Kelussia odoratissima extract against a number of isolated bacteria of the enterobacteriaceae family such as Escherichia coli, Shigella flexneri and Salmonella Typhi.Methods : After culturing the three bacteria and preparing the microbial suspension, Kelussia odoratissima extract was prepared by ethanol and methanol (Dimethyl Sulfoxide). MBC (Minimum Bactericidal Concentration) and MIC (Minimum Inhibitory Concentration) tests were determined with Kelussia odoratissima extract.Results : According to the results, the highest growth retardation halo for Shigella flexneri, Salmonella typhi and Escherichia coli was obtained by diluting the whole methanolic extract of Kelussia odoratissima.Conclusion : Both ethanolic and methanolic extracts have a deterrent effect on the growth of Shigella flexneri, Salmonella typhi, and Escherichia coli. This study showed that the inhibitory effect of methanol extract was greater than that of ethanol extract.

کلیدواژه ها:

Kelussia odoratissima ، Ethanol ، Methanol and extract