۲۰۱۹-nCoV enents in Qom province, Iran

سال انتشار: 1399
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 145

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شناسه ملی سند علمی:

MEDISM21_230

تاریخ نمایه سازی: 23 مرداد 1400

چکیده مقاله:

Background and Aim : Recently, a new coronavirus (۲۰۱۹-nCoV), has emerged in the region of Wuhan (China) as a cause of severe respiratory infection in humans. This short report investigate a virus genome analysis and symptoms of disease in Qom province.Methods : The literature search was performed by finding related case-control articles from the PubMed, Google Scholar, Web of Science, Scopus, databases and patients referred to general hospitals in Qom Province.Results : ۲۰۱۹-nCoV is closely related (with ۸۸% identity) to two bat-derived severe acute respiratory syndrome (SARS)-like coronaviruses but were more distant from SARS-CoV (about ۷۹%) and MERS-CoV (about ۵۰%). The envelope spike (S) protein mediates receptor binding and membrane fusion and is crucial for determining host tropism and transmission capacity. Different symptoms were seen: Having no underlying chronic medical conditions but reported fever, Significant changes in the lung, Fever and cough, Shortness of breath or difficulty breathing, Muscle aches, Chills, Sore throat, Runny nose, Headache, Chest pain, vomiting and diarrhea, and Different pattern of Chest CT scan immagings from first day to the fifteenth day. Also, RT-PCR method and chest CT scan are the best diagnostic methods.Conclusion : This is the first reportation in Qom province. These data along with data from our study could clarify the transmission dynamic of the ۲۰۱۹-nCoV supporting infection control policy during the ongoing epidemic.

نویسندگان

Mohaddeseh Khalilian

Department of Microbiology, Faculty of Biological Sciences, Shahid Beheshti University, Tehran, Iran

Hasan Vahidi Emami

Department of Microbiology, Faculty of Veterinary Medicine, University of Tehran, Iran