Seroprevalence of brucellosis in Famenin city, Hamadan, west of Iran : Famenin Brucellosis Cohort Study

Background and Aim : Brucellosis is endemic in Iran with higher level of endemicity at western areas including Hamadan province. This study aims to define the seroprevalence of brucellosis and it,s risk factors in general population of Famenin, a city of Hamadan province, in west of Iran.Methods : This survey was conducted on ۲۳۶۷ participants in Famenin and its villages from September to November, ۲۰۱۶. After receiving written consent from subjects, demographic information was entered into the questionnaires and also ۱۰cc blood samples were taken from the participants. Blood samples were sent to the Core facility of Hamadan University of Medical Sciences and were tested using Wright and ۲ME kits (Pasteur Institute, Iran) for brucellosis serological detection. The seroprevalence of brucellosis was reported as percentage with ۹۵% confidence interval.Results : ۲۳۶۷ individuals with the mean age (SD) of ۳۴.۶ (۲۰.۹) (range: ۲ to ۹۵) years were enrolled. Of these, ۱۰۶۰ (۴۴.۸%) were men and ۱۶۱۰ (۶۸.۰%) lived in rural areas. The seroprevalence of brucellosis according to the Wright titer, equal or greater than ۱:۸۰, was ۶.۶% (۹۵% CI: ۵.۶۲% -۷.۶۶%). The corresponding prevalence based on ۲ME titers, equal or greater than ۱:۴۰ in the subjects with positive Wright test was ۳۷.۲% (۹۵% CI: ۲۹.۵%-۴۴.۸۴%). We saw a significant association between the incidence of brucellosis and the occupation (p<۰.۰۰۱) and type of contact with livestock (p= ۰.۰۰۹) as two important risk factors.Conclusion : The seroprevalence of brucellosis in Famenin population was considerable. Contact with livestock, animal husbandry, farming and history of brucellosis were risk factors for brucellosis infection.

کلیدواژه ها:

Brucellosis ، Seroprevalence ، Zoonotic Infectious Disease ، Famenin ، Iran