A review on West African Ebola epidemic dynamics models

Background and aims: The world is threatened by disease outbreak that reaches a public health emergency of international concern, studies to inform public and agencies for effective containment strategy are necessary. Several studies provided vital information of the dynamics and control of Ebola epidemic outbreak in West Africa. Methodologies and techniques in those researches have to be reviewed for purposes of synthesis of published research in this area, insight into how to carry out similar studies and future research direction.Methods: In this report we adopted a thematic review of recent studies that covered topical issues of epidemic model theories and applications used in Ebola investigations. Models for studying severity and prevalence of the disease, statistics, and growth threshold parameters, efficacy of intervention measures, and uncertainty and sensitivity analysis of the disease models were reviewed.Results: In ۱۹۶۶, ۶.۳۴% of the national total population was over ۶۰ years compared to Ebola dynamics is widely investigated, covering topical epidemiological problems that involves mathematical model for purposes of providing quantitative information for epidemic control decisions.Conclusion: Mathematical models play great role in modelling epidemics,. Therefore, a comprehensive survey of mathematical theories, methodologies and models in Ebola growth studies will provide standpoints for future epidemic investigation.

کلیدواژه ها:

Ebola ، Epidemic model ، Epidemic optimal control ، Sensitivity analysis