Lung cancer risk assessment of exposure to respirable crystalline silica in Iran

Exposure to crystalline silica is known as the lung cancer in human. There are a few studies on estimation of lung cancer risk of crystalline silica in workplaces So, the aim of this study was to lung cancer risk assessment of occupational exposure to crystalline silica in Iran. For overview, databases including Web of Sciences, Scopus, PubMed, Google Scholar, and SID (Scientific Information Database), were searched. All of the available studies in the field of occupational exposure to crystalline silica were provided. According to the cumulative exposure, risk of silicosis-related mortality in exposed workers was estimated. Exposure to crystalline silica was ranged from a geometric mean of ۰.۰۹۵۴ to ۰.۲۷۸۴mg/m(۳), which washigher than that recommended standard exposure limit by ACGIH ۰.۰۲۵mg/m(۳)), NIOSH and OSHA (۰.۰۱mg/m(۳)).The relative risk of death from silicosis was in the((۳)۰.۰۵mg/m)range of ۱ to ۶۳.۶۳ per thousand people and the risk of lung cancer in workers was rangedfrom ۳۶ to ۱۰۴ per thousand. Workers in the mines and cement manufacturing had highestand lowest of the risk of lung cancer, respectively. Result indicated that workers are at considerable cancer risk due to exposure to crystalline silica, the .exposure control programs need to be implemented in workplaces to decrease concentration of crystalline silica

کلیدواژه ها:

Crystalline silica ، Exposure ، systematic review ، Lung cancer risk ، Iran