Inclusion of hydrazinophthalazine insight into the cavity of β-cyclodextrin: A study of surface tension and UV-vis spectroscopy
محل انتشار: نشریه آسیایی شیمی سبز، دوره: 5، شماره: 2
سال انتشار: 1400
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 202
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شناسه ملی سند علمی:
JR_AJGC-5-2_003
تاریخ نمایه سازی: 18 خرداد 1400
چکیده مقاله:
Surface tension, conductivity, and ultraviolet spectroscopic methods have been employed to study the dimensional fit molecular encapsulation of hydrazinophthalazine hydrochloride insight into the cavity of β-cyclodextrin in aqueous media. The equilibrium constant and ۱:۱ stoichiometry of the complex has been analyzed by surface tension (plot against reciprocal of concentration), and Job’s plot (drawn from UV-vis data). The binding constants computed from the tensiometric and spectroscopic method were found to be ۵۹.۹۱ μM-۱ and ۱۲.۰۲-۹۶.۵۸ μM-۱, respectively, that return the comfort zone of the results. The noteworthy upshot has also come out from standard Gibbs energy for inclusion complex formation. The free energy for inclusion complex is negative and lower in magnitude than adsorption by ۶.۱۱ kJ mol-۱. ۱HNMR and SEM picture also certified the formation of the inclusion complex. The results demonstrated that the driving force for formation of the inclusion complex inside the bucket-like cavity of β-cyclodextrin was a combination of hydrophobic effect and reduction of the surface energy, while in adsorption is only hydrophilic effect.
کلیدواژه ها:
Hydrazinophthalazine hydrochloride β ، cyclodextrin Surface tension UV ، vis spectroscopy Inclusion complex
نویسندگان
Samir Das
Department of Chemistry, University of North Bengal, Darjeeling-۷۳۴۰۱۳, India
Paramita Karmakar
Department of Chemistry, University of North Bengal, Darjeeling-۷۳۴۰۱۳, India
Mahendra Nath Roy
Department of Chemistry, University of North Bengal, Darjeeling-۷۳۴۰۱۳, India
Deepak Ekka
Department of Chemistry, Cooch Behar Panchanan Barma University, Coochbehar-۷۳۶۱۰۱, India