Maternal Serum Ferritin Level in Prediction of Mothers with Appropriate-For-Gestational-Age (AGA), Small-For-Gestational Age (SGA), and Intrauterine Growth Restriction (IUGR)
محل انتشار: مجله بین المللی کودکان، دوره: 9، شماره: 7
سال انتشار: 1400
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 189
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شناسه ملی سند علمی:
JR_INJPM-9-7_011
تاریخ نمایه سازی: 17 خرداد 1400
چکیده مقاله:
Background Fetal growth restriction is one of the main causes of perinatal mortality that can be predicted by ferritin. We aimed to evaluate the role of ferritin in prediction of mothers with Appropriate-for-gestational-age (AGA), Small-for-gestational age (SGA) and intrauterine growth restriction (IUGR). Materials and Methods: In this cohort study, we screened ۷۳ mothers with gestational ages of ۳۲-۳۴ weeks. If amniotic fluid index (AFI) was normal and there was no circulation defect, the fetuses were classified in SGA group and in case of presence of oligohydramnios or circulation defect; they were classified in IUGR group. Also, fetuses with normal growth were classified in AGA group. We evaluated the serum ferritin, hemoglobin, and iron of the mothers. Moreover, we evaluated the levels of placenta ferritin, Hb, and hematocrit in the delivery room. Results: In this study, ۲۸ patients were categorized in AGA group, ۱۵ patients in SGA group and ۳۰ patients in IUGR group. Mean weight of all infants was ۲۲۱۰.۶۰ ± ۹۳۲.۷۷ grams. Also, the mean AFI of all infants was ۹.۸۱ ± ۳.۵۹. The mean ferritin level of all mothers was ۳۰.۲۹ ± ۱۰.۸۰ and IUGR group had the highest and AGA group had the lowest ferritin levels (P=۰.۰۱۵). Maternal ferritin (µg/l) (Sen: ۶۷.۹%, Sp: ۶۱.۹%), maternal hematocrit (%) (Sen: ۷۰%; Sp: ۶۲.۸%,) and maternal Hb (Sen: ۷۰%, Sp: ۶۵.۱%,) could predict IUGR. Conclusion Increased (>۳۴ µg/l) and decreased (
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نویسندگان
Tahereh Behrouzi-Lak
Reproductive Health Research Center, Department of Infertility, Urmia University of Medical Sciences, Urmia, Iran.
Mahdieh Mortazavi
Urmia University of Medical Sciences, Urmia, Iran.
Shabnam Vazifeshenas
Maternal and Childhood Obesity Research Center, Urmia University of Medical Sciences, Urmia, Iran.