Study of the bactericidal and bacteriostatic effects of olive oil, sesame oil and their synergism on Pseudomonas aeruginosa in vitro

سال انتشار: 1396
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 274

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شناسه ملی سند علمی:

JR_JHPH-3-4_001

تاریخ نمایه سازی: 12 خرداد 1400

چکیده مقاله:

Background and aims: Nosocomial infections are common problems in developing and developed countries. One of the pathogens that causes these infections is Pseudomonas aeruginosa. According to the antibiotical resistance of this bacteria, It is essential to find new treatments like new herbal medicine. This study was aimed to determine in vitro antibacterial effects of sesame oil, olive oil and their synergism on P. aeruginosa.Methods: In this experimental study, first, olive oil and sesame oil were obtained by cold-pressing assay. Then, P.aeruginosa ATCC ۲۷۸۵۳ was prepared from Iranian Research Organization for Science and Technology. Oils and their mixture with the same proportion were made in concentrations from ۲ to ۱۰۲۴ mg/ml and the antibacterial character of these oils on P.aeruginosa was investigated by broth micro dilution method and then the amounts of the MIC and the MBC were demonstrated.Results: The MIC of olive oil, sesame oil and their synergism on P.aeruginosa were reported; ۱۶ mg/ml, ۱۲۸ mg/ml and ۱۲۸ mg/ml and the MBC of these oils were indicated; ۶۴ mg/ml, ۵۱۲ mg/ml and ۵۱۲ mg/ml, respectively.Conclusion: This study showed that sesame oil, olive oil and their synergism can inhibit bacterial growth. Olive oil has more antibacterial effect on this bacteria than sesame oil and their synergism. So, we conclude that there was no synergistic effect in these oils.

نویسندگان

reza heidari soureshjani

Students Research Committee, Shahrekord University of Medical Sciences, Shahrekord, Iran.

reza alipoor

Students Research Committee, Fasa University of Medical Sciences, Fasa, Iran.

Seyed_Saadat Gholami

Medical student, Students Research Committee, Yasouj University of Medical Sciences, Yasouj, Iran.

Reza hashemi hafshejani

Students Research Committee, Shahrekord University of Medical Sciences, Shahrekord, Iran.

Arefeh kiyani

Students Research Committee, Shahrekord University of Medical Sciences, Shahrekord, Iran.

Yaghoob Madmoli

Nursing Student, students research committee, Dezful University of Medical Sciences, Dezful, Iran.

Abolfazl Gholipour

Assistant professor, Department of Public Health, Shahrekord University of Medical Sciences, Shahrekord, Iran.

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