Antibacterial Effects Studu of Nanofluid Containing Carbon Nanotubes on Pseudomonas Aeruginosa Infections

سال انتشار: 1399
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 272

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شناسه ملی سند علمی:

CIGS16_225

تاریخ نمایه سازی: 14 اردیبهشت 1400

چکیده مقاله:

Background and Aim: Background: Pseudomonas aeruginosa is an opportunistic pathogen that exploits the immune system of individuals with malignant infections and toxins. Pseudomonas aeruginosa causes urinary tract infections, respiratory tract, skin inflammation, soft tissue infections and a variety of systemic infections, especially in burn patients and those with tissue damage. Nowadays, the antibacterial effects of Carbon Nano Tubes (CNTs) have been shown in numerous studies, and these nanotubes can be very useful in drug delivery and also they have unique properties in the fight against multidrug-resistant bacterial infections. Aim: In this study, the antibacterial effects of Nano fluid containing carbon nanotubes on Pseudomonas aeruginosa were investigated.Methods: Methods: Standard and pathogen strains of Pseudomonas aeruginosa were treated under different doses of Nanofluid (NF) containing Functionalized Multi-wall CNTs (MWCNTs) with a concentration of ۲mg/ml, NF and Antibiotic alone and NF with Antibiotic. Then the MIC and MBC tests observation were performed for all treated strains.Results: Results: In this study, it was observed that multiwalled carbon nanotubes can have antimicrobial effects on Pseudomonas aeruginosa and their resistance to ciprofloxacin and imipenem antibiotics was significantly reduced. However, to obtain more accurate results, we carry out specialized cellular and molecular research .Conclusion: Conclusion: For the first time, the effects of nanofluids containing carbon nanotubes on the antibiotic resistance of Pseudomonas aeruginosa have been investigated to prevent nosocomial infections.

کلیدواژه ها:

Keywords: Pseudomonas aeruginosa ، Functionalized Multi-wall Carbon Nanotubes ، Nanofluid ، antibiotic resistance.

نویسندگان

Mojgan Sheikhpour

Department of Mycobacteriology and Pulmonary Research, Pasteur Institute of Iran, Tehran, Iran.

Vahid Amiri

Department of Mycobacteriology and Pulmonary Research, Pasteur Institute of Iran, Tehran, Iran.