Prevalence of Epilepsy in Iran Using Meta-Analysis and Systematic Review

Background and Objective: Epilepsy is a one of the most common diseases causing many problems in Iran. Hence, this study was an attempt to assess the prevalence of epilepsy using meta-analysis and systematic review methods in Iran. Materials and Methods: Nine Iranian papers published in time period of ۲۰۰۲ to ۲۰۱۰ were selected using valid keywords and searching in the SID, Google scholar, PubMed and Elsevier databases. The heterogeneity of samples was dealt with using the I۲ index. Results: In this study, the data of ۷۷۲۳ patients was used and nine papers were selected for meta-analysis among the published papers. The total prevalence of epilepsy was calculated to be ۵% (۹۵% confident interval (CI): (۲%-۸%) in Iran. The prevalence of epilepsy in central, northern and eastern areas of Iran was found to be ۵% (۹۵% CI, ۲%-۸%), ۱% (۹۵% CI, -۱%-۳%) and ۴% (۹۵% CI, ۳%-۱۱%), respectively. Somatic diseases and inheritance were the common risk factors of epilepsy with the percentage of ۳۹% (۹۵% CI, ۱۵%-۶۲%) and ۲۶% (۹۵% CI, ۹%-۴۲%), respectively. Conclusion: The findings in our study indicated a ۵% more prevalence of epilepsy in Iran until ۲۰۱۰ in comparison to similar countries though this trend decreased with increasing age. Geographic area evidence showed a remarkable prevalence in the Center, East and North of the country and physical illnesses comprised the major risk factors. References ۱-Valizadeh L, Akbarbegloo M, Zamanzadeh V, Rahiminia E, Caleb Ferguson F. The relationship between psychosocial care and attitudes toward illness in adolescents with epilepsy. Epilepsy Behav. ۲۰۱۳ ۲۷: ۲۶۷-۷۱. ۲- Papavasilion AS, Kotsalis C, Paraskevoulakos E, Karaqouis P, Pizou C, Baziqou H. Intravenous midazolam in convulsive status epilepticus in children with pharmacoresistant epilepsy. Epilepsy Behav. ۲۰۰۹ ۱۴: ۶۶۱-۴. ۳- Pei-min Yu, Ding Ding G, Lan Xu, et al. 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Keywords: Epilepsy ، Iran ، Prevalence ، Meta-analysis ، Systematic review