The Relation Between Serum Zinc Level and Febrile Seizures in Children Admitted to Zanjan Valie-Asr Hospital

Background and Objective: Febrile seizures (FS) are the most common seizures seen in childhood with a prevalence of 2-14% in different societies. This study was carried out regarding the possibility of the relationship between serum zinc levels and occurrence of FS. Materials and Methods: 117 children ranging from 6 months to 5 years were divided into four groups: FS (n=39), febrile patients with no seizures (FNS) (n=40), control group of afebrile patients with no seizures (AFNS) (n=32), and patients with seizures without fever (n=6). After completion of a questionnaire and obtaining blood, serum zinc levels were measured. Data was analyzed using SPSS software. Results: The mean serum zinc levels in 39 FS patients was 75.67 mcg/dl, 40 febrile patients with no seizure had a mean serum zinc level of 87.58 mcg/dl. 32 afebrile patients with no seizure had a mean serum zinc level of 89.06  mcg/dl and in 6 afebrile patients with seizure; the mean serum zinc level was 96/67 mcg/dl. The serum zinc level in FS patients was significantly lower than the other groups (p=0.002 and p=0.001), whereas the 3 other groups had no significant difference (P= 0.971). Conclusion: Regarding the high incidence of hypozincaemia in FS, low serum zinc levels may be associated with the occurrence of FS.

کلیدواژه های The Relation Between Serum Zinc Level and Febrile Seizures in Children Admitted to Zanjan Valie-Asr Hospital:

Febrile Seizures ، Serum Zinc Leuel ، Febrile Patients ، Zanjan