Evaluation of the Relationship between Maternal Preeclampsia and Lung Maturation of Preterm Infants in Zanjan- Valiasr Hospital

Evaluation of the Relationship between Maternal Preeclampsia and Lung Maturation of Preterm Infants in Zanjan- Valiasr Hospital Fekri S۱, Mohamadiyan F۱, Ghanbari M۲ ۱ Dept of Gynecologic Diseases, Zanjan University of Medical Sciences, Zanjan, Iran ۲ Zanjan University of Medical Sciences, Zanjan, Iran Corresponding Authorchr('۳۹')s Address: Dept of Gynecologic Diseases, Zanjan University of Medical Sciences, Zanjan, Iran E-mail: FEKRI۴۳@zums.ac.ir Received: ۲۹ Sep, ۲۰۰۸ Accepted: ۱۷ Jan, ۲۰۰۹ Background and Objective: There are many studies showing that fetal lung maturation in complicated pregnancies like preeclampsia is accelerated. Lung maturation in this condition is due to glucocorticoid secretion in response to stress. There are also con-tradictory opnions about fetal lung maturation in preeclampsia. In this study the relationship between lung maturation in preterm infants and maternal preeclampsia was investigated. Materials and Methods: This case – control study was applied to ۹۶ preterm infants with Respiratory Distress Syndrome (RDS) as the case group and ۹۶ preterm infants without RDS as the control group in Zanjan- Valiasr hospital during the years ۲۰۰۴-۲۰۰۵. Both groups were similarized for age, sex, weight and type of delivery. Patientchr('۳۹')s data were obtained from their medical records and were analyzed by T and X۲ tests. Results: In ۳۱ preterm infants with RDS (۳۱.۶%), and in ۲۳ preterm infants without RDS (۲۳.۴%), the mother was preeclamptic. This difference was not statistically significant. Conclusion: According to the results of present study, the risk of RDS in preterm infants of preeclamptic mothers is not lower than the non preeclamptic mothers therefore fetal lung maturation is not accelerated in maternal preeclampsia.

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Key words: Preeclampsia ، Preterm infants ، Lung maturation