The Prevalence of Zinc Deficiency in Children with Febrile Seizure
محل انتشار: مجله پزشکی بالینی، دوره: 8، شماره: 1
سال انتشار: 1400
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 359
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شناسه ملی سند علمی:
JR_RCM-8-1_001
تاریخ نمایه سازی: 6 اردیبهشت 1400
چکیده مقاله:
Introduction: A febrile seizure (FS) occurs in ۲-۴% of children aged ۶ months to ۵ years. A simple febrile seizure is the most common seizure in children. According to the evidence, both genetic and environmental factors affect the occurrence of this condition. The purpose of this study was to determine the association between zinc deficiency and sociological factors, and febrile seizures. Methods: This case-control study evaluated ۱۳۶ children at ۲۲ Bahman Hospital of Gonabad, Iran, from July ۲۰۱۵ to March ۲۰۱۸. We selected ۳۶ children aged ۶ months to ۵ years with febrile seizures as the case group and ۱۰۰ febrile children without a seizure, in the same age range, as the control group. The demographic characteristics, place of residence, family history of seizures, and zinc serum level were recorded, and data were analyzed by frequency, average, and standard deviation, and Chi-square statistical tests. The odds ratios were calculated by logistic regression with a ۹۵% confidence level. SPSS version ۲۲.۰ was used for statistical analysis. Results: Totally, ۳۸.۸% of the cases with FS and ۵.۰% of the febrile children without seizure had a zinc deficiency. The serum zinc level in the case group was ۷۵.۴۴ ± ۱۶.۹۸ µgr/dL and in the control group was ۱۰۰.۲۷ ± ۲۴.۲۳ µgr/dL (P < ۰.۰۰۱). The odds ratio of zinc deficiency in the patients with FS compared to the febrile children without convulsion was ۱.۰۶۹ (۱.۰۴۵-۱.۱۵۱). Conclusion: Children with FS are more susceptible to have zinc deficiency than those febrile but without a seizure. Therefore, zinc deficiency could be a preventable and treatable risk factor for FS.
کلیدواژه ها:
نویسندگان
Fargol Nabavi
Student Research Committee, School of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran
Javad Akhondian
Department of pediatric neurology, Ghaem hospital, Mashhad University of Medical Sciences, Mashhad, Iran
Sepideh Karkon Shayan
Social development and Health promotion Research Center, Gonabad University of Medical Sciences, Gonabad, Iran
Sepideh Babaniamansour
Department of Pathology, School of Medicine, Islamic Azad University Tehran Faculty of Medicine, Tehran, Iran
Raheleh Derafshi
Department of Pediatrics, Medicine Faculty, Gonabad University of Medical Sciences, Gonabad, Iran
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