Selective Oxidation of Thiols to Disulfides by Some Zwitterammonium Bromide Perbromide

A very simple and mild reaction is described for the efficient coupling of thiols at room temperature by N,N’-dibenzyl-N,N,N’,N’- tetramethylenediamonium bromide perbromide (DBTMEDABP), N,N’- dibenzyl-1,4- diazabicyclo[2,2,2] octane bromide perbromide (DBDABCOBP), o-xylylen bis(triethylamonium bromide perbromide) (XTEABP) under solvent free and solvent condition.

کلیدواژه ها:

thiols ، disulfide ، oxidative coupling ، bromide perbromide ، solvent free condition