A mild, expedient, solventless synthesis of bis(indolyl)alkanes using nano silica sulfuric acid as a reusable catalyst

Nano silica sulfuric acid nSSA) was found to be a mild, efficient and reusable solid acid catalyst in electrophilic substitution reaction of indoles with carbonyl compounds to affordthe corresponding bis(indolyl)alkanes in excellent yields undersolvent-free conditions.

کلیدواژه ها:

Silica sulfuric acid ، bis(indolyl)alkanes ، aldehydes ، ketones ، indole