Synthesis of 2-amino-4H- benzo[h]chromenes in the presence of Fe3O4/SiO2/urea nanocatalyst

Nanoparticle Fe3O4-supported catalysts can be simply separated from the reaction mixture by an external permanent magnet. This strategy is typically more effective than filtration or centrifugation that become annoying for such small nanoparticles.1,2 Herein, we report the synthesis of 2-amino-4H-benzo[h]chromene-3-carbonitrile 4 from the reaction between aromatic aldehyde 1, malononitrile 2 and 1-naphthol 3 in the presence of Fe3O4/SiO2/urea catalyst. All synthesized compounds are stable solids their structures were determined on the basis of their mass spectrum, 1H and 13C NMR and IR spectroscopic data.

کلیدواژه ها:

Multicomponent reactions ، Nano catalyst ، Fe3O4/SiO2/urea ، 2-Amino-4H- benzo[h]chromene-3-carbonitrile.