Efficient synthesis of symmetrical anhydrides by cross dehydrogenative coupling of aldehydes over CuFe2O4 nanoparticles

Carboxylic anhydrides are an important class of organic compounds used as versatile reagents in the preparation of carboxylic acid derivatives. They are also employed as reactive intermediate in various types of reactions.1 Anhydrides are important, but less abundant in nature. Therefore, their synthesis is significant for organic chemists. In recent years, considerable attention has been attracted to the cross-dehydrogenative coupling (CDC) reactions because of their atom economy, step-economy, and the outstanding role in the formation of C–C, and C–X (X=heteroatom) bonds.2 Aldehydes and other readily available materials are advantageous in CDC reactions.3 These compounds have been used in significant organic transformations.4 Due to copper is superior activity, in this study we report a novel CDC based approach for the synthesis of symmetrical anhydrides through oxidative activation of sp2 C–H bond of aldehydes using TBHP as an oxidizing agent and copper ferrite nanoparticles (CuFe2O4 NPs) as the catalyst.

کلیدواژه ها:

CuFe2O4 NPs ، Anhydride ، Cross dehydrogenative coupling ، Magnetic Nanocatalyst ، Recyclable.