Synthesis of 1-(α-aminoalkyl)-2-naphthols using 3-methyl-1-sulfonic acid imidazolium trichloridocuprate

One of the important classes of organic compounds is 1-(α-aminoalkyl)-2-naphthols which called Betti bases compounds.1 The synthesis of substituted Betti base derivatives is an important part of organic chemistry because of their attractive catalytic 2 and biological properties.3 The typical Betti reaction is a three-component reaction between an aldehyde, ammonia or urea and β-naphthol. Although, variations have been made to prepare Betti base derivatives through by quilinols, naphthols, alkyl amines to exchange ammonia, uncatalyzed in water, sulfanilic acid-functionalized silica-coatedmagnetite nanoparticles, N-heteroaryl amino naphthol and the addition of naphthols to preformed iminium salts has to be attained.4 In the presented work, we have prepared 3-methyl-1-sulfonic acid imidazolium trichloridocuprate as a new catalyst for the synthesis of 1-(α-aminoalkyl)-2-naphthols which exhibits many important properties (Fig. 1).

کلیدواژه ها:

Multi component reactions ، 1-(α-aminoalkyl)-2-naphthol ، Solvent-free.