Synthesis, characterization and catalytic evaluation of NiFe2O4@SiO2@glucose amine for the synthesis of novel derivatives of thiazolidine-4-ones
محل انتشار: بیست و هفتمین کنفرانس شیمی آلی ایران
سال انتشار: 1398
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 138
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شناسه ملی سند علمی:
ISOC27_218
تاریخ نمایه سازی: 19 اسفند 1399
چکیده مقاله:
Thiazolidine -4-ones exhibit antitubercular, antimicrobial, antioxidant and antifungal activity and can be applied as COX-1 inhibitor, bacterial enzyme MurB inhibitor, non-nucleozide anzyme inhibitor of HIV-RT and antihistaminic agent.1 For this reason, synthesis of novel derivatives of thiazoline-4-ones have attracted a lot of interest. Traditional heterogeneous catalysts are limited in the nature of their active sites and their reaction scope abilities. Soluble organic catalysts can catalyse a variety of reaction more than traditional solid catalysts but suffer from their inability to be recycled. For this reason, synthesis of organic and inorganic hybrid composite to utilize the organic moiety as the active site and the solid to provide avenue to recovery and recyclability is attractive. 2In continuation of our previous work 3, herein, we specifically address the synthesis and usage of organic-inorganic hybrid materials based on NiFe2O4@SiO2-propyl@glucose amine magnetic nanoparticle as catalyst for the synthesis of new generation of thiazolidine-4-ones. All of organic compounds are new and characterized by IR, 1H NMR, 13 C NMR, Mass and elemental analysis.
کلیدواژه ها:
نویسندگان
Leila Zare Fekri
Department of Chemistry, Payame Noor University, PO Box ۱۹۳۹۵-۳۶۹۷ Tehran, Iran
Shohreh Zeinali
Ghadr Institute of higher education, department of pharmaceutical chemistry, Koochesfahan, Guilan, Iran