Cobalt phthalocyanine based catalyst promoted the facile synthesis of cyclohexa-1,3-dienamines

Metal phthalocyanines as macrocyclic complexes, due to easy preparation and chemical stability are broadly used in organic functional group transformations. These structures, due to their elegant optical and electrical characteristic, have found various applications in material science. On the other hands, multisubstituted cyclohexa-1,3-dienamines are privileged structure which represent varied pharmaceutical applications in medicinal chemistry. These molecules, can applied as useful intermediates for synthesis of cyclophanes to create a large molecular cavity and host-guest complexes.1-2In this investigation, we presented a multicomponent reaction manner for the synthesis of multisubstituted cyclohexa-1,3-dienamines through the reaction of aryl ketones, aldehydes and malononitrile in the presence of cobalt phthalocyanine based catalyst (Figure 1).

کلیدواژه ها:

Cobalt phthalocyanine ، Cyclohexa-1 ، 3-dienamines ، Multicomponent reaction