Scar-free skin healing

Introduction: Every scar tells a story — about the time you fell from your bike or the day you burnt your hand. Every scar also tells about the body’s amazing ability to heal itself. But it’s not perfect. Unfortunately, many times when our skin is wounded, the cut isn’t clean, the healing conditions are not ideal and we end up with a scar. The tissue will try to reorganize, and the scar may appear to soften, but the skin may never completely return to its original state — particularly if the cut extends beyond the epidermis, the skin’s outer layer. Skin cells regenerate from the bottom up, with a turnover time of roughly one month. We can think of the epidermis as a staircase, where the bottom stair is the base of the epidermis and the top stair is exposed to the air. New epidermal cells are formed by cell division at the bottom of the staircase. To make room for these new cells, the older epidermal cells are pushed upward toward the top of the staircase. The oldest cells die and fall off.Description: In the context of this overview, 25 articles were used between the years 2010 through the end of 2018 using the Keywords of PubMed, Google scholar search engines.Discussion and conclusion: A number of potential therapies have been developed to reduce scar formation in cutaneous wounds based on differences between the process of adult and fetal wound healing. The ideal approach to eliminate scar formation after skin injury is to use a pro-regenerative matrix along with growth factors and cell types that induce regeneration rather than repair.

کلیدواژه ها:

Skin ، Wound Healing ، Scar