Resveratrol and Gliomas: Where are we standing?

Gliomas are well-known brain and spinal cord tumors. These tumors are a heterogeneous group of brain tumors with different biological and clinical features. Surgery and chemotherapy are known as current therapeutic platform in the treatment of various types of gliomas. Despite different advances in the therapeutic approaches in the treatment of gliomas, several limitations are associated with them. Hence, finding and developing new therapeutic option are necessary. Plans medicine are new horizons which could be employed as new anti-cancer agents. Resveratrol is well known natural compounds that can be used as therapeutic agent alone or in combination with other chemotherapy drugs. Resveratrol shows pharmacology activities such as anti-cancer, anti-aging, anti-inflammatory, chemotherapeutic, cardio protective, and neuroprotective action. Several studies indicated that resveratrol exerts therapeutic effects on glioma cells. Given that this natural compound exerts its therapeutic impacts on gliomas via targeting different physiological and pathological events such as apoptosis, growth, angiogenesis, and metastasis. Herein, we summarized the anti-gliomas effects of resveratrol.