Isolation of methicillin-resistant Staphylococcus aureus from urine in patients referred to Ahvaz Pasteur Laboratory

Introduction & Objectives: Antibiotic resistance in Staphylococcus aureus infections as a major public health problem causes the prevalence of resistant urinary tract infections in clinics and hospitals. Towards this purpose, we analyzed the urine sample of patients at Pastour clinic in Ahwaz between August 2016 and August 2017.Materials & Methods: 132suspected urine samples were evaluated by biochemical methods including catalase, mannitol fermentation, coagulase and DNAse for the presence of staphylococcus aureus. The sensitivity test was performed using disc diffusion method for common antibiotics. Data were analyzed using descriptive statistics.Results: The results of biochemical tests confirmed the presence of 84 different strains of Staphylococcus aureus in the urine of the studied patients. The maximum antibiotic resistances were related to penicillin with 100% and cefoxitin (methicillin) with 90.47% and the minimum antibiotic resistances was related to nitrofurantoin with 4.76% In addition, other antibiotics including trimethoprim-sulfomethoxazole, tetracycline and vancomycin antibiotics showed 88.09%, 83.33% and 10.71% resistance, respectively.Conclusion: Methicillin-resistant Staphylococcus aureus strains (MRSA) are one of the leading causes of nosocomial infections that may even lead to patient death. The results of this study indicate the prevalence of resistant strains of this bacterium in Ahvaz as well as the need to increase hospital hygiene and use appropriate antibiotics with low resistance to prevent further spread of these dangerous strains.

کلیدواژه ها:

Methicillin-resistant Staphylococcus aureus ، Urinary Tract Infection ، Antibiotic Resistance ، Ahvaz